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15 July 2024
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Dogs & puppies
Infectious Disease

Brucella

The UK has recently seen an increase in the number of dogs presenting with symptomatic Brucella canis. There are several species of Brucella which affect a wide range of animal species, including people. We have been screening cattle for Brucella infection for a number of years and have a national protocol in place to protect people from cross infection from cattle or cattle products such as milk. Previously Brucella canis was not considered to be a significant risk however the increase in UK dogs infected with Brucella canis and the few cases where humans have become infected have changed how we need to manage the risks. 

If your dog has spent any time living outside the UK (imported from abroad, travelled outside the UK with you or others, or immigrated into the UK) then they could be at increased risk of infectious agents that we rarely see in the UK. Many dogs show minimal to no associated clinical signs for months or years following infection (some will never show signs). These dogs may subsequently spread infection to non-travelled dogs and, in rare cases, people, typically to those living with them or with very close contact.

The current rules on importing dogs into the UK only provide for risk reduction against Rabies (a viral infection) and the Echinococcus tapeworm (a parasitic worm infection) – both of which can cause life-threatening disease in people. Other diseases, including Brucella, are not covered by current import legislation.

Dependent on country(ies) visited we may require a screening blood test for exposure to Brucella canis prior to any routine inpatient (“elective” / routine) care such as neutering or dentistry. Pending negative test results we will wear gloves and aprons when handling your pet.

Screening for other infectious diseases your dog may have been exposed to while travelling may also be recommended. NB: dependent upon timing of entry into the UK repeat testing may be recommended / required.

Recommended testing for imported dogs

Dogs that are sick due to Brucella canis infection normally present with the following clinical signs:

  • Neck or spinal pain, sometimes leading to lameness 
  • Swelling and/or pain in the testes / scrotum
  • Purulent discharge from the penis/prepuce or vulva
  • Infertility (i.e. failure to become pregnant or successfully sire offspring) or abortion (usually late term), still birth, and fading puppies
  • Eye pain or inflammation (uveitis)

Any dog that presents to the clinic with infertility, abortion / still birth, or that is subsequently found to have unexplained testes/scrotal swelling, unexplained uveitis, or evidence on imaging of inflammatory vertebral disc disease (“discospondylitis”) causing neck / spinal pain or lameness, will be required to screen for Brucella canis exposure, even where there is no identifiable history of travel or contact with travelled dogs. NB: as many infected dogs have subclinical disease (i.e. show no / minimal clinical signs) – requirements for testing are also based upon other risk factors (e.g. travel)

The cost of Brucella canis screening is typically around £90. This involves a simple blood sample, collected by a vet or vet nurse. An in-house lateral flow test (LFT) normally gives a same day result which can allow some treatments to go ahead. The remaining sample is sent to APHA (part of the government Department for Environment and Rural Affairs) for confirmatory tests which can take up to 10 days to give results. 

Our team will wear PPE to protect themselves from risk whilst handling the patient and samples. 

Information on Brucella canis

Brucella canis is endemic in many countries, including parts of the EU. The incidence in the UK is generally considered to be very low. It is mostly transmitted dog-to-dog by sexual contact. The most common clinical signs affect the sex organs but sometimes the infection can cause inflammation elsewhere in the body, most commonly the spine causing severe spinal pain and paralysis. 

Infected dogs pose a risk to humans, with vets (particularly during surgery) and lab staff (handling blood and urine samples) at higher risk. Although rare, the consequences of human infection can be very severe and life changing. In recent years, there have been two cases of human infection by Brucella canis in the UK following exposure to infected dogs.

Infected dogs may not show any clinical signs and infection can be lifelong. It is not normally possible to clear the infection – even with long courses of antibiotics. Unfortunately, the only sure way to prevent spread of infection to other dogs or humans is to avoid all contact with infected dogs or humanely euthanise the infected dog. 

What should we do about Brucella canis?

Infection is rare in the UK but higher if the dog has lived in a country where the infection is more prevalent, especially if they spent time as an un-neutered stray. This is why we request Brucella canis screening tests in dogs that have a history of living in certain countries, even if very historical, prior to being able to offer some inpatient and laboratory services. 

It is helpful if we can take samples for testing before the patient is ill, as treatment may have to be delayed until results are back, which may worsen outcomes. 

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